Anti-androgens effect of Diane-35. Cyproterone acetate has the ability to competitively bind to receptors of the natural male sex hormones androgens. Cyproterone reduces the influence of androgens, produced in the female body, which allows to treat diseases caused by excessive formation of androgens or an increased susceptibility to them. The therapeutic effect of Diane-35 is manifested in healing acne, preventing the formation of new acne, reduction of excessive sebaceous excretions of the scalp and face.
Contraceptive effect of Diane-35. Diane-35 inhibits ovulation and changes the viscosity of cervical mucus. Along with anti-androgenic properties, cyproterone has gestagen activity, simulating the properties of progesterone. Cyproterone inhibits the secretion of pituitary gonadotrophic hormones and inhibits ovulation. Ethinylestradiol increases central and peripheral effect of cyproterone on ovulation, retains a high viscosity of cervical mucus, making it difficult for sperm to penetrate the uterus and helps to ensure a reliable contraceptive effect.